Chromosomal breakpoint mapping by arrayCGH using flow-sorted chromosomes
نویسندگان
چکیده
منابع مشابه
Chromosomal breakpoint mapping by arrayCGH using flow-sorted chromosomes.
Despite the recent completion of the human genome project, the mapping of disease-related chromosomal translocation breakpoints and genes has remained laborious. Here, we describe a novel and rapid procedure to map such translocation breakpoints using flow-sorted chromosomes in combination with array-based comparative genomic hybridization (arrayCGH). To test the feasibility of this approach, w...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 2003
ISSN: 0736-6205,1940-9818
DOI: 10.2144/03355dd03